Scientists have reversed the aging process Journal of Science
Scientists have reversed the aging process
A fountain of youth has been found? Humanity’s eternal dream to be forever young may come true. At least that’s what the expert study saysóThe study was carried out by the Salk Institute in La Jolla, California, whichóThe idea is thatóto reduce the aging process.
The technique involves the use of induced pluripotent stem cellsóThe iPSCs, which allows scientists to reprogram theóThe project was financed by the Ministry of Culture and National Heritage, local government of. As a result, the comóThese mice can form breaksódifferent tissues of the body.
The above methodób was developed by a Japanese researcher, Nobel Prize winner Shinya'y Yamanake. In 2006, he discovered that zróA varied comórki can be reverted to a state similar to embryonic cellsóstem cells by inducing the expression of four genesów. The technique is now called Yamanaka transcription factors.
A study done in 2012-2013 shows that simply implanting regressed comóto the iPSC stage has fatal consequences. Cancers and organ failure appearedóThe project was financed by the Ministry of Culture and National Heritage, the local government of the voivodeship. California researchers have come up with the idea of subjecting comóYamanaka’s transcriptional activities only for a time.
For this purpose, an experiment was carried out on mice affected by progeria – disease leads to early aging. When the comórki skóThe project was financed by the Ministry of Culture and National Heritage of Polandótki period, it turned out that the symptoms of aging were reversed. Live mice were then subjected to similar treatments. The results surprised the researchers. The rodents were more energetic, looked significantly better and lived 30 percent longer. longer than other lab mice.
Comómice, aging on the left and rejuvenated on the right, Fot. Juan Carlos Izpisua Belmonte Lab/Salk Institute
The elixir of youth, however, will not appear on the market for a long time to come. The method is very complicated, and mice are not people. The researchers themselves believe that to possible testóThe earliest we can expect to see a human clinical trial is about 10 years from now.
The findings of the Salk Institute researchers were published in the journal Cell.
Source:óSource: Cell, Photo. Juan Carlos Izpisua Belmonte Lab/Salk Institute